September 01, 2005

Us and them

The BBC reports that researchers have completed the sequencing and analysis of the chimpanzee genome. It's long been held that chimps are humanity's closest living relatives, having diverged from a common ancestor only about 7 million years ago, but now we can see just how close that relationship is.
The study shows that our genomes are startlingly similar. We differ by only 1.2% in terms of the genes that code for the proteins which build and maintain our bodies. This rises to about 4%, when non-coding or "junk" DNA is taken into account.

The long-term goal of the project is to pinpoint the genetic changes that led to human characteristics such as complex language, walking upright on two feet, a large brain and tool use.
As the study’s lead author, Tarjei Mikkelsen of the Broad Institute at MIT, says:
We still do not have in our hands the answer to a most fundamental question: What makes us human? But this genomic comparison dramatically narrows the search for the key biological differences between the two species.
Nature magazine is commemorating the project’s completion with a special web feature on Pan troglodytes, including some previously-unseen footage of chimpanzee behaviour.